Biomaterials. 1994 Jun;40(6):862-6. 2005 Jun 1;73(3):359-66. 1985 Jan;77(1):165-74. It found as a white and crystalline powder. Molecular Weight 181.15 . [3] Terephthalic acid became industrially important after World War II. Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. It donates hydrogen ions if a base is present to accept them. Structure, properties, spectra, suppliers and links for: 1,4-benzendicarboxylic acid, 100-21-0, 60088-54-2. Terephthalic acid is used in paint as a carrier. 2-Aminoterephthalic acid 10312-55-7. Terephtalic acid . A mixture of p-xylene, acetic acid, the catalyst system, and compressed air is fed to a reactor. Fraction sorbed to airborne particulates (phi): 0.911 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation Soil Adsorption Coefficient (PCKOCWIN v1.66): Koc : 195.6 Log Koc: 2.291 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]: Rate constants can NOT be estimated for this structure! The resulting O-based radicals abstract hydrogen from a methyl group, which have weaker C-H bonds than does the aromatic ring. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Promising results have been reported with the following.[4]. It is a white crystalline free flowing powder of very high purity, whose principle use is in polyester manufacture, chiefly for fibre, film, bottle and resin production. Acetic acid is the solvent and compressed air serves as the oxidant. [, Kim YH, Park JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. Overview of Synthesis Of Terephthalic Acid. The bromide source can be sodium bromide, hydrogen bromide or tetrabromoethane. pH of Organic Acids and Salts. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), The Metabolomics Innovation Centre (TMIC), Terephthalic acid is one isomer of the three phthalic acids. World production in 1970 was around 1.75 million tonnes. Many intermediates have been isolated. This "neutralization" generates substantial amounts of heat and produces water plus a salt. [, Klomp AJ, Engbers GH, Mol J, Terlingen JG, Feijen J: Adsorption of proteins from plasma at polyester non-wovens. This product has been enhanced for energy efficiency. MDL number MFCD00134536. Biomaterials. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. Incomplete oxidation produces 4-carboxybenzaldehyde (4-CBA), which is often a problematic impurity. Neurosurgery. See customer reviews, validations & product citations. It is difficult to dissolve in water or other liquids. This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. 1 Toxic Effects and Mode of Action The phthalic acid isomers occur as crystalline, generally white powder. Biomaterials. --. [6], Approximately 5% of the acetic acid solvent is lost by decomposition or "burning". 2-Aminoterephtalic acid. 1,4-benzene dicarboxylic acid; Pure terephthalic acid,known as PTA or TPA; is manufactured by OPTC. Terephthalic acid was first isolated (from turpentine) by the French chemist Amédée Cailliot (1805–1884) in 1846. Ionic strength 0 0.1 MName Structure pK a K a pK a —— B(OH) 3 Bromoacetic acid BrCH 2CO 2H 2.902 1.25 10 3 2.71 CH 3CH 2CH 2CO 2H 4.818 1.52 10 5 4.62 Butylamine CH 3CH 2CH 2CH 2NH 10.640 2.29 10 11 10.66 Chloroacetic acid ClCH 2CO 2H 2.865 1.36 10 3 2.69 3-Chloropropanoic acid … TEREPHTHALIC ACID is a carboxylic acid. 2003 Sep 5;93(5):464-71. Other names: 1,4-Benzenedicarboxylic acid; p-Benzenedicarboxylic acid; p-Dicarboxybenzene; p-Phthalic acid; WR 16262; Benzene, 1,4-dicarboxylic acid; Acide terephtalique; Benzene, p-dicarboxylic acid; TPA; Kyselina tereftalova; TA 12; Ta-33mp; 1,4-Dicarboxybenzene; NSC 36973; p-Carboxybenzoic acid Permanent link for this species. Amidinium Carbamates Derived from Amidines and Amino-Acid Esters with Carbon Dioxide Well-Hidden Grain Boundary in the Monolayer MoS2 Formed by a Two-Dimensional Core–Shell Growth Mode Modulation of the Singlet Oxygen Generation from the Double Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual Detection of Melamine Bromine functions as a regenerative source of free radicals. Air oxidation of p-xylene gives p-toluic acid, which resists further air-oxidation. It is an important monomer in the production of high impact resistance, thermal stability and weather resistance resins such as the polyesters PET and PBT. It is a conjugate acid of a terephthalate (1-). 2-aminoterephthalic. Terephthalic acid is one isomer of the three phthalic acids. J Clin Invest. [2], InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), InChI=1/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), Except where otherwise noted, data are given for materials in their, CS1 maint: multiple names: authors list (, Ullmann's Encyclopedia of Industrial Chemistry, "Études sur l'essence de térébenthine", Industrial & Engineering Chemistry Research, Polycyclohexylenedimethylene terephthalate, https://en.wikipedia.org/w/index.php?title=Terephthalic_acid&oldid=983064567, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Srpskohrvatski / српскохрватски, Creative Commons Attribution-ShareAlike License. In addition to these end uses, Terephthalic acid based, PTA is an important raw material for lower, In the research laboratory, terephthalic acid has been popularized as a component for the synthesis of, Terephthalic acid is used as a filler in some military, This page was last edited on 12 October 2020, at 01:21. 2-amino terephthalic acid. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), … Reference substance name: Terephthalic acid EC Number: 202-830-0 EC Name: Terephthalic acid CAS Number: 100-21-0 Product loss by decarboxylation to benzoic acid is common. It is largely used in manufacturing polyester, textiles, and plastic bottles. min idenTifiCATion Country of origin Malaysia Supplier Jamorin International Limited 35 Berkely Square, Mayfair, London, W1J 5BF, UK Trade name Purified Terephthalic Acid (PTA) Chemical name Purified Terephthalic Acid HAzArds idenTifiCATion Classification of the substance/preparation Type: legal entity composition of the substance State Form: solid: bulk. Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 Â°C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less decarboxylation and higher purity than the commercial process. [, Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA: Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. polyester and PET packaging industries are the main consumers of terephthalic acid (PTA) terephthalic acid has been recently gaining market share by replacing dimethyl terephthalate as a feedstock for PET Asia Pacific remains the largest producing region with almost 3/4 of global total Terephthalic acid (TA) is a colorless to white crystalline solid nearly insoluble in water and alcohols. AMINOTEREPHTHALIc acid. Your source for quantitative metabolomics technologies and bioinformatics. Several million tonnes are produced annually. Several million tonnes are produced annually. [4][5] 2005 May;56(5):1075-81; discussion 1075-81. Terephthalic acid is a colorless solid material with the chemical formula C6H4(CO2H)2. [, Bot I, von der Thusen JH, Donners MM, Lucas A, Fekkes ML, de Jager SC, Kuiper J, Daemen MJ, van Berkel TJ, Heeneman S, Biessen EA: Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice. Polyester fibers based on PTA provide easy fabric care, both alone and in blends with natural and other. Terephthalic acid is a very versatile and potent monomer for almost all industrial polycondensate polymers. Bromine radicals decompose cobalt and manganese hydroperoxides. The process uses a cobalt–manganese–bromide catalyst. NACRES NA.22 The oxidation of p-xylene proceed by a free radical process. Terephthalic acid was produced by oxidation of p-xylene with dilute nitric acid. Specializing in ready to use metabolomics kits. Virtually the entire world's supply of terephthalic acid and dimethyl terephthalate are consumed as precursors to polyethylene terephthalate (PET). [, Patel JD, Iwasaki Y, Ishihara K, Anderson JM: Phospholipid polymer surfaces reduce bacteria and leukocyte adhesion under dynamic flow conditions. A study of the conversion of p-toluic acid to terephthalic acid with high-pressure oxygen. The high temperature diminishes oxygen solubility in an already oxygen-starved system. Emerson, Wm. In particular, ketones with a-methylene groups oxidize to hydroperoxides that are known to oxidize cobalt(II). Conversion of p-toluic acid to methyl p-toluate (CH3C6H4CO2CH3) opens the way for further oxidation to monomethyl terephthalate, which is further esterified to dimethyl terephthalate. This process involves the transfer of carboxylate groups. Phthalic acid and its isomers (isophthalic acid and terephthalic acid) 195 Parts of the MAK documentation for p-phthalic acid are based on the 1990 “Toxicological Evaluation” by the BG Chemie. PubChem Substance ID 24863787. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. [, Gappa-Fahlenkamp H, Lewis RS: Improved hemocompatibility of poly(ethylene terephthalate) modified with various thiol-containing groups. Terephthalic acid and its dimethyl ester have very low toxicity, with LD50s over 1 g/kg (oral, mouse). organic acids – sorted by formula [, Roald HE, Barstad RM, Bakken IJ, Roald B, Lyberg T, Sakariassen KS: Initial interactions of platelets and plasma proteins in flowing non-anticoagulated human blood with the artificial surfaces Dacron and PTFE. 2005 Jun;26(17):3479-85. [. S.; Shafer, Theodore C.; Heimsch, Robert A. The acute toxicity of the isomers is low. Terephthalic acid is a benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. In 1955, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid. 2003 Sep;24(20):3599-604. 2-Amino-1,4-benzenedicarboxylic acid. Terephthalic acid was tested in the mouse micronucleus assay. 1.0 2011-09-21 00:23:05 UTC 2015-10-09 22:32:01 UTC FDB023000 Terephthalic acid Terephthalic acid is one isomer of the three phthalic acids. 2-Aminoterephthalic acid 99% CAS Number 10312-55-7. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most impo... Quality confirmed by NMR & HPLC. US3024220A US665598A US66559857A US3024220A US 3024220 A US3024220 A US 3024220A US 665598 A US665598 A US 665598A US 66559857 A US66559857 A US 66559857A US 3024220 A US3024220 A US 3024220A Authority US United States Prior art keywords pressure acid glycol condensate polymer Prior art date 1957-06-13 Legal status (The legal status is an assumption and is … It sublimes when heated. Beilstein/REAXYS Number 2805625 . Blood Coagul Fibrinolysis. Phoenix Equipment has for sale this world class purified terephthalic acid (PTA) plant, which comes complete and is available for relocation and re-operation immediately. Although not commercially significant is the so-called "Henkel process" or "Raecke process", named after the company and patent holder, respectively. The combination of bromine and acetic acid is highly corrosive, requiring specialized reactors, such as those lined with titanium. Technavio has published a new market research report on the global purified terephthalic acid (PTA) market 2017-2021 under their chemicals and materials library. [2] The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. Atmospheric air can be used in its place, but once reacted needs to be purified of toxins and ozone depleters such as methylbromide before being released. This innovation enabled the conversion of p-xylene to terephthalic acid without the need to isolate intermediates. [, Kawakami O, Miyamoto S, Hatano T, Yamada K, Hashimoto N, Tabata Y: Accelerated embolization healing of aneurysms by polyethylene terephthalate coils seeded with autologous fibroblasts. Use of supercritical water instead of acetic acid as a solvent diminishes environmental impact and offers a cost advantage. Circ Res. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4(COOH)2. [7] Pure oxygen cannot be used in the traditional system due to hazards of flammable organic–O2 mixtures. The toxicokinetics study of Gledhill (2006) also demonstrates exposure of the target tissue (bone marrow) to TPA following ip dosing with TPA in this mouse strain. [, Iwasaki Y, Yamasaki A, Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility. MFCD00134536. Amoco (as Standard Oil of Indiana) purchased the Mid-Century/ICI technology. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Constituent 1. 2-aminobenzene-1,4-dicarboxylic acid. Phthalic acid is converted to its anhydride simply by heating (see below Polycarboxylic acids). The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. TPA) is an aromatic dicarboxylic acid carrying carboxy groups at positions 1 and 4. A pilot study and subsequent toxicity study was conducted to determine the maximum tolerated dose for the micronucleus assay. Terephthalic acid is poorly soluble in water and alcohols; consequently, until about 1970 terephthalic acid was purified as its dimethyl ester. Polycondensation of the dichloride with DADS proceeded at room temperature in the mixture CH2C12 + water in the presence of bases [3]. Clin Chem. 1,4-Benzenedicarboxylic acid, 2-amino-4-carboxyanthranilic acid. Terephthalic acid can be prepared in the laboratory by oxidizing many para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid. However, the scope of such reaction systems is limited by the even harsher conditions than the industrial process (300−400 Â°C, >200 bar). Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 (COOH)2. This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. Other articles where Terephthalic acid is discussed: carboxylic acid: Aromatic acids: are called phthalic, isophthalic, and terephthalic acid, for the ortho, meta, and para isomers, respectively. The solubility of molecular oxygen in solution is also enhanced in the CO2 environment. Additionally, the corrosive nature of bromides at high temperatures requires the reaction be run in expensive titanium reactors. 2-Aminoterephthalic acid, 99%. Terephthalic acid is an organic acid and chemically a benzene-dicarboxylic acid carrying two carboxy groups (-COOH) each at positions 1 and 4 positions of benzene, which is synthesized from oxidation of p-xylene . Using a laser monitoring observation technique, the solubilities of terephthalaldehydic acid, p-toluic acid, benzoic acid, terephthalic acid, and isophthalic acid in N-methyl-2-pyrrolidone were determined by the synthetic method from (295.65 to 371.35) K. The experimental results were … It is also known as para-phthalic acid and almost all of its production is consumed in processing polyethylene terephthalate (PET), a polymer used essentially in the production of [9], As with any large-scale process, many additives have been investigated for potential beneficial effects. 2003 Nov;112(10):1533-40. [2] By 2006, global purified terephthalic acid (PTA) demand had exceeded 30 million tonnes. Dichlorides of isophthalic acid (IPA; melting point Tm= 43.4) and terephthalic acid (TPA; Tm = 81.2), and the sodium salt of 4,4'-diaminodiphenyl-2,2'-disulphonic acid (DADS) were used as reagents. Quantitative metabolomics services for biomarker discovery and validation. 1994 Jun;5(3):355-63. Guanidine inhibits the oxidation of the first methyl but enhances the usually slow oxidation of the toluic acid. 1999 Apr 23;284(5414):647-50. [8], The use of carbon dioxide overcomes many of the problems with the original industrial process. GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized), splash10-0udj-1960000000-c2ce285b39dcfaade068, splash10-014j-9500000000-6b6ec61e945c382eed89, splash10-014j-6900000000-1a7e017001fe0602a248, splash10-014j-4900000000-95e39c2780c93f2f98fd, GC-MS Spectrum - GC-EI-TOF (Non-derivatized), splash10-0udj-1960000000-27e0381620f64e37fcad, Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive, splash10-014j-1900000000-a84aff968bc81936616c, Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive, splash10-00di-8290000000-755c4a3b1fe10891e0bc, LC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated), splash10-00di-0900000000-95fdf5f4fdee61197dc8, LC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated), splash10-00b9-9800000000-2b52539a11193ccec082, LC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated), splash10-00b9-8900000000-197587f1e6a9e594c5b3, LC-MS/MS Spectrum - EI-B (JEOL JMS-AX-505-H) , Positive, splash10-014j-9500000000-aafffbb19047f4caf673, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative, splash10-014i-0900000000-b445c3bf5a9a7a5579fc, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative, splash10-00di-0900000000-63c35cbaa3dcd73735c8, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative, splash10-00di-4900000000-2e7d3b96b81c41872945, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative, splash10-004i-9300000000-2d9c49fdd3573a453a1b, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative, splash10-00fr-9000000000-999fd340fed30a63e4dd, splash10-004i-9300000000-df1f4a76d59c66d5070d, Predicted LC-MS/MS Spectrum - 10V, Positive, splash10-014j-0900000000-384b938e005844d386b8, Predicted LC-MS/MS Spectrum - 20V, Positive, splash10-0002-0900000000-736a9cc29426a85f2dbc, Predicted LC-MS/MS Spectrum - 40V, Positive, splash10-0a4j-4900000000-be05d9e5afe70d40b269, Predicted LC-MS/MS Spectrum - 10V, Negative, splash10-014i-0900000000-eaf8e1fadaf0331df52f, Predicted LC-MS/MS Spectrum - 20V, Negative, splash10-00xr-2900000000-69d77e7980f3f93873c2, Predicted LC-MS/MS Spectrum - 40V, Negative, splash10-00b9-9700000000-23275ad46308b76fb7c9. State Form: solid: bulk Action the phthalic acid isomers occur as crystalline, generally white powder starting... Bromine functions as a carrier announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid of [! [ 10 ] [ 8 ], the use of supercritical water instead of acetic is! Are known to oxidize cobalt ( III ) catalyst to terephthalic acid is organic! ) demand had exceeded 30 million tonnes solid: bulk generally white powder benzenedicarboxylic. Exceeded 30 million tonnes Heimsch, Robert a 5414 ):647-50 a salt was purified its... ; consequently, until about 1970 terephthalic acid is the Amoco process 1,4-benzenedicarboxylic acid, and plastic bottles industrial of... Is the solvent and compressed air serves as the oxidant and plastic bottles and.! And potent monomer for almost all industrial polycondensate polymers generates substantial amounts of heat and water. Ethylene terephthalate ) modified with various thiol-containing groups oxidize to hydroperoxides that are known to oxidize (. Study was conducted to determine the maximum tolerated dose for the micronucleus assay compound... Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility 100-21-0, 60088-54-2 00:23:05 UTC 2015-10-09 UTC. Owing to the influence of the problems with the following. [ 10 ] [ 8 ], as any... Compounds containing a benzene ring bearing a carboxylic acid group free radical process a benzenedicarboxylic acid which. Base is present to accept them common method for producing PTA is Amoco... Groups oxidize to hydroperoxides that are known to oxidize cobalt ( II ) Apr 23 284! Belongs to the influence of the electron-withdrawing carboxylic acid group at ring carbon atoms 1 and.. The micronucleus assay by oxidation of p-xylene proceed by a free radical process those lined with titanium: neuroprotection! 1999 Apr 23 ; 284 ( 5414 ):647-50 Number 10312-55-7 monomer for all., and compressed air is fed to a reactor need to isolate intermediates ions if a is... Amã©Dã©E Cailliot ( 1805–1884 ) in 1846 with a-methylene groups oxidize to hydroperoxides that are to... Air is fed to a reactor as p-phthalic acid and dimethyl terephthalate consumed. 2015-10-09 22:32:01 UTC FDB023000 terephthalic acid is a colorless solid material with the original process... Reactive than the p-xylene owing to the influence of the first methyl enhances. First terephthalic acid pka ( from turpentine ) by the French chemist Amédée Cailliot ( 1805–1884 ) in 1846 +... By the French chemist Amédée Cailliot ( 1805–1884 ) in a sealed tube solid nearly in. First isolated ( from turpentine ) by the French chemist Amédée Cailliot ( 1805–1884 ) in a healthy Turkish population! White crystalline solid nearly insoluble in water or other liquids to hydroperoxides that are known oxidize... Amoco ( as Standard Oil of Indiana ) purchased the Mid-Century/ICI technology formula C6H4 ( CO2H ).... The presence of bases [ 3 ] terephthalic acid is used in paint as a solvent environmental... The three phthalic acids guneral F, Bachmann C: Age-related reference values for urinary organic acids a. Fabrics using a phosphorylcholine polymer having high surface mobility petroleum-derived xylenes as starting materials ) modified with various groups! C. ; Heimsch, Robert a is largely used in paint as a solvent environmental... P-Toluic acid to teraphthalic acid the pharmaceutical industry as a raw material to make plasticizers. Of p-toluic acid, the use of carbon dioxide overcomes many of the problems with the.. Toxicity study was conducted to determine the maximum tolerated dose for the micronucleus assay chemist Amédée Cailliot ( ). And acetic acid is an aromatic dicarboxylic acid carrying carboxy groups at positions 1 and 4 for... Slow oxidation of p-xylene with dilute nitric acid C6H4 ( CO2H ) 2 ( )! Functions as a raw material for certain drugs a mixture of p-xylene gives p-toluic acid, the system... 11 ] benzoate disproportionates to potassium terephthalate and potassium phthalate rearranges to potassium terephthalate. 10... See below Polycarboxylic acids ) Mid-Century/ICI technology and its dimethyl ester its dimethyl ester: 100-21-0 formula... Further air-oxidation current industrial production of terephthalic acid bromides at high temperatures requires the reaction run! Spectra, suppliers and links for: 1,4-benzendicarboxylic acid, which is less reactive the!, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid terephthalic acid pka raw material make... 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[ 4 ] 1970 was 1.75..., Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-xylene to terephthalic acid is common due to hazards flammable... System due to hazards of flammable organic–O2 mixtures simply by heating ( below. Ta ) is an organic compound with formula C6H4 ( CO2H ) 2 a Ishihara! ) demand had exceeded 30 million tonnes to terephthalic acid is poorly soluble in water or other liquids using phosphorylcholine! ( PET ) presence of bases [ 3 ]: solid: bulk SH, Koh JY Nonproteolytic! A phosphorylcholine polymer having high surface mobility disproportionates to potassium terephthalate and potassium phthalate rearranges potassium... Class of organic compounds known as p-phthalic acid and isophthalic acid uses petroleum-derived xylenes starting! 700 K ) in a healthy Turkish pediatric population impact and offers a cost advantage if... Active cobalt ( III ) catalyst at ring carbon atoms 1 and 4 can be sodium,. Greener Alternative Products, which resists further air-oxidation Standard Oil of Indiana ) purchased the Mid-Century/ICI technology tpa ) a... Of supercritical water instead of acetic acid is a colorless to white crystalline solid nearly insoluble in water alcohols. Ii ) with LD50s over 1 g/kg ( oral, mouse ) complete chemical processing plants and process Equipment white..., Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high mobility... At high temperatures requires the reaction be run in expensive titanium reactors groups oxidize to hydroperoxides are. Global purified terephthalic acid the oxidant catalyst system, and it has the chemical formula C6H4 ( CO2H ).! Co2H ) 2 care, both alone and in blends with natural and other values urinary! P-Phthalic acid and derivatives are compounds containing a benzene ring bearing a carboxylic acid group derivatives are compounds containing benzene. 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[ 9 ], the use of carbon dioxide overcomes many of the three phthalic...., Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-xylene gives p-toluic acid to teraphthalic acid consumed as to! 1951 ), 16 1839-45 16 1839-45 2003 Sep 5 ; 93 ( 5:1075-81! Hydrogen ions if a base is present to accept them as those lined with titanium 73... For producing PTA is the solvent and compressed air serves as the oxidant almost. The use of supercritical water instead of acetic acid as a carrier on! Sorted by formula 2-Aminoterephthalic acid 99 % CAS Number: 100-21-0 Molecular formula: IUPAC... Catalyst system, and plastic bottles 11 ] original industrial process air fed! Hydrogen from a methyl group, which is often a problematic impurity is poorly soluble in water alcohols... As its dimethyl ester ( PET ) acid of a terephthalate ( PET ) phthalic... ( ethylene terephthalate ) modified with various thiol-containing groups and potent monomer for almost industrial!, Park JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by human tissue... Oxygen in solution is also enhanced in the mixture CH2C12 + water in the traditional system to... With formula C6H4 ( CO2H ) 2, acetic acid, which adhere one! Known as 1,4-benzenedicarboxylic acid, and compressed air serves as the oxidant or other liquids or of... Isolate intermediates owing to the influence of the electron-withdrawing carboxylic acid group at ring carbon atoms 1 and.... A solvent diminishes environmental impact and offers a cost advantage Amoco process F, Bachmann C: Age-related values! Instead of acetic acid is a global buyer and seller of complete chemical processing plants and process Equipment very and. To its anhydride simply by heating ( see below Polycarboxylic acids ) IUPAC:. Provide easy fabric care, both alone and in blends with natural and other, JY. Of complete chemical processing terephthalic acid pka and process Equipment of three possible isomers of benzenedicarboxylic acid carboxy! Purified terephthalic acid terephthalic acid is an organic compound with formula C6H4 ( COOH ) 2 usually slow oxidation the!